???????: ??????? ????? ??????? ? ??????? ??? ?????? ?? ?????? ? ?????????? ???? ?????? ?????????? ????? ??? ??? ????? ?? ?? ??????? ???????: ????? ????? ? ?????, ??? ??? ????? ?? ????? ?? ??????, ??? ?????.The dosing tips down below, hence, can only be regarded as prompt methods to what is in fact a number of clinical decisions as time passes withi